NEET PG & INI-CET - Pre-Clinical Sciences (Anatomy, Physiology & Biochemistry)

Clinical Biochemistry & Nutrition question bank (Medical Biochemistry)

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Q1.

In clinical evaluation regarding urea cycle regulation and enzyme deficiency (Case Vignette #2): Which of the following observations or mechanisms is most accurate?

(A)

Argininosuccinate synthetase deficiency is X-linked dominant

(B)

Ornithine transcarbamylase (OTC) deficiency is X-linked recessive with elevated orotic acid

(C)

Carbamoyl phosphate synthetase I (CPS I) deficiency increases urine orotic acid

(D)

All urea cycle disorders are transmitted in an autosomal dominant manner

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Q2.

In clinical evaluation regarding vitamin b12 (cobalamin) biochemical role (Case Vignette #4): Which of the following observations or mechanisms is most accurate?

(A)

Cofactor for alanine transaminase and glycogen phosphorylase

(B)

Cofactor for methionine synthase and methylmalonyl-CoA mutase

(C)

Cofactor for pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase

(D)

Cofactor for prolyl hydroxylase and dopamine beta-hydroxylase

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