NEET PG & INI-CET - Pre-Clinical Sciences (Anatomy, Physiology & Biochemistry)

Metabolism of Carbohydrates & Lipids question bank (Medical Biochemistry)

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Q1.

In clinical evaluation regarding rate-limiting step of fatty acid synthesis (Case Vignette #2): Which of the following observations or mechanisms is most accurate?

(A)

Carnitine Palmitoyltransferase-1 (CPT-1)

(B)

HMG-CoA Reductase, activated by glucagon

(C)

Fatty Acid Synthase, activated by malonyl-CoA

(D)

Acetyl-CoA Carboxylase (ACC), activated by citrate and inhibited by palmitoyl-CoA

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Q2.

In clinical evaluation regarding urea cycle regulation and enzyme deficiency (Case Vignette #4): Which of the following observations or mechanisms is most accurate?

(A)

Argininosuccinate synthetase deficiency is X-linked dominant

(B)

Carbamoyl phosphate synthetase I (CPS I) deficiency increases urine orotic acid

(C)

Ornithine transcarbamylase (OTC) deficiency is X-linked recessive with elevated orotic acid

(D)

All urea cycle disorders are transmitted in an autosomal dominant manner

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